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Article
Open AccessThe P2Y1 receptor in the colonic myenteric plexus of rats and its correlation with opioid-induced constipation
This study was designed to explore the expression changes of P2Y1 receptors in the distal colonic myenteric layer of rats. An opioid induced constipation(OIC) rat model was generated by intraperitoneal (i.p) inje...
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Article
The relative contributions of soft tissue mass components as risk or protective factors of non-alcoholic fatty liver disease in children
Several body components are known to be associated with non-alcoholic fatty liver disease (NAFLD) in children. However, the relative contributions of soft tissue mass components as risk or protective factors o...
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Article
Open AccessNotch signaling pathway: architecture, disease, and therapeutics
The NOTCH gene was identified approximately 110 years ago. Classical studies have revealed that NOTCH signaling is an evolutionarily conserved pathway. NOTCH receptors undergo three cleavages and translocate i...