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  1. No Access

    Article

    Three-phase Enriched Environment Improves Post-stroke Gait Dysfunction via Facilitating Neuronal Plasticity in the Bilateral Sensorimotor Cortex: A Multimodal MRI/PET Analysis in Rats

    The three-phase Enriched Environment (EE) paradigm has been shown to promote post-stroke functional improvement, but the neuronal mechanisms are still unclear. In this study, we applied a multimodal neuroimagi...

    Yun Lu, Ziyue Lin, Mingcong Li, Yuming Zhuang, Binbin Nie… in Neuroscience Bulletin (2024)

  2. Article

    Open Access

    Altered metabolic connectivity within the limbic cortico-striato-thalamo-cortical circuit in presymptomatic and symptomatic behavioral variant frontotemporal dementia

    Behavioral variant frontotemporal dementia (bvFTD) is predominantly considered a dysfunction in cortico-cortical transmission, with limited direct investigation of cortical-subcortical transmission. Thus, we a...

    Li Liu, Min Chu, Binbin Nie, Deming Jiang, Kexin **e… in Alzheimer's Research & Therapy (2023)

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  3. Article

    Open Access

    A longitudinal 18F-FDG PET/MRI study in asymptomatic stage of genetic Creutzfeldt–Jakob disease linked to G114V mutation

    Pathogenic prion protein may start to deposit in some brain regions and cause functional alterations in the asymptomatic stage in Creutzfeldt–Jakob disease. The study aims to determine the trajectory of the br...

    Min Chu, Zhongyun Chen, Binbin Nie, Li Liu, Kexin **e, Yue Cui… in Journal of Neurology (2022)

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  4. Article

    Open Access

    Reconfigured metabolism brain network in asymptomatic microtubule-associated protein tau mutation carriers: a graph theoretical analysis

    Studies exploring topological properties of the metabolic network during the presymptomatic stage of genetic frontotemporal dementia (FTD) are scarce. However, such knowledge is important for understanding bra...

    Li Liu, Min Chu, Binbin Nie, Lin Liu, Kexin **e, Yue Cui… in Alzheimer's Research & Therapy (2022)

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  5. No Access

    Article

    Gray matter reduction related to decreased serum creatinine and increased triglyceride, Hemoglobin A1C, and low-density lipoprotein in subjects with obesity

    Altered brain volume and metabolic variables have been found in subjects with obesity. However, the role of metabolic parameters in gray matter volume (GMV) has been poorly investigated. This study aimed to in...

    Han Shan, Panlong Li, Hua Liu, Binbin Nie, **aolong Yin, Tianhao Zhang… in Neuroradiology (2019)

  6. No Access

    Article

    An Automatic Method for Generating an Unbiased Intensity Normalizing Factor in Positron Emission Tomography Image Analysis After Stroke

    Positron emission tomography (PET) imaging of functional metabolism has been widely used to investigate functional recovery and to evaluate therapeutic efficacy after stroke. The voxel intensity of a PET image...

    Binbin Nie, Shengxiang Liang, **aofeng Jiang, Shaofeng Duan… in Neuroscience Bulletin (2018)

  7. No Access

    Article

    Abnormal Metabolic Connectivity in Rats at the Acute Stage of Ischemic Stroke

    Stroke at the acute stage is a major cause of disability in adults, and is associated with dysfunction of brain networks. However, the mechanisms underlying changes in brain connectivity in stroke are far from...

    Shengxiang Liang, **aofeng Jiang, Qingqing Zhang, Shaofeng Duan… in Neuroscience Bulletin (2018)