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Article
Competing risks analysis of external versus internal radiation in patients with hepatocellular carcinoma after controlling for immortal time bias
In cohort studies on liver cancer, there are often immortal time bias and interference of competing risk events. This study proposes to explore the role of internal and external radiotherapy for hepatocellular...
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Article
Expression and clinicopathological significance of EED, SUZ12 and EZH2 mRNA in colorectal cancer
Enhancer of zeste 2 (EZH2), embryonic ectoderm development (EED), and suppressor of zeste 12 homolog (SUZ12), the key component of polycomb repressive complex 2, are of great importance in human cancer pathoge...
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Article
TFAP2E hypermethylation was associated with survival advantage in patients with colorectal cancer
Hypermethylation of TFAP2E (AP-2E) is associated with the chemotherapy-resistant in patients with colorectal cancer (CRC), but its implications on prognosis directly remain unknown. This study was aimed to inv...
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Article
Phase II trial of gefitinib in pretreated Chinese women with advanced non-small-cell lung cancer
A phase II clinical trial was performed to evaluate the efficacy and safety of gefitinib on pretreated Chinese female non-small-cell lung cancer (NSCLC) patients. Chinese female patients with locally advanced ...
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Article
Adult stem cells and cancer stem cells: tie in or tear apart?
Stem cell research is one of the new frontiers of medical science. Because of the unique self-renewable ability and powerful potential to differentiate, stem cells can be viewed as the mother of all cells in t...
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Article
MAGE-1 and related MAGE gene expression may be associated with hepatocellular carcinoma
Purpose: The possibility of tumor rejection antigen, encoded by the MAGE-1 gene, being a target for immunotherapy in hepatocellular carcinoma (HCC) patients and the cloning of the full-length cDNA of this gene f...
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Article
The targeted expression of the human interleukin-2/interferon α2b fused gene in α-fetoprotein-expressing hepatocellular carcinoma cells
This study explores the use of a liver-specific albumin promoter and a tumor-specific α-fetoprotein (AFP) enhancer to achieve the regulated expression of the cytokine interleukin-2/interferon α2b (IL-2/IFNα2b...