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  1. Article

    Open Access

    PET imaging of P2X7R in the experimental autoimmune encephalomyelitis model of multiple sclerosis using [11C]SMW139

    Non-invasive imaging of the activation status of microglia and the ability to identify a pro- or anti-inflammatory environment can provide valuable insights not only into pathogenesis of neuro-inflammatory and...

    Wissam Beaino, Bieneke Janssen, Esther Kooijman… in Journal of Neuroinflammation (2020)

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  2. Article

    Open Access

    Purinergic receptors P2Y12R and P2X7R: potential targets for PET imaging of microglia phenotypes in multiple sclerosis

    Microglia are major players in the pathogenesis of multiple sclerosis (MS) and may play a dual role in disease progression. The activation status of microglia in vivo is highly dynamic and occurs as a continuu...

    Wissam Beaino, Bieneke Janssen, Gijs Kooij… in Journal of Neuroinflammation (2017)

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