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  1. Article

    Open Access

    Neoadjuvant chemotherapy alters the balance of effector to suppressor immune cells in advanced ovarian cancer

    At diagnosis, tumor-infiltrating lymphocytes (TILs) are prognostic in epithelial ovarian cancer (EOC). We recently demonstrated that neoadjuvant chemotherapy (NACT) significantly increased stromal TILs. Here,...

    Alexandra Leary, Catherine Genestie, Félix Blanc-Durand in Cancer Immunology, Immunotherapy (2021)

  2. Article

    Open Access

    The PI3K/Akt/mTOR pathway in ovarian cancer: therapeutic opportunities and challenges

    The phosphatidylinositol 3 kinase (PI3K) pathway is frequently altered in cancer, including ovarian cancer (OC). Unfortunately, despite a sound biological rationale and encouraging activity in preclinical mode...

    Bianca Cheaib, Aurélie Auguste, Alexandra Leary in Chinese Journal of Cancer (2015)