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381 Result(s)
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Article
Correction to: Association Between a Failed Prominence Eruption and the Drainage of Mass from Another Prominence
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Article
Open AccessNotoginsenoside R1 promotes Lgr5+ stem cell and epithelium renovation in colitis mice via activating Wnt/β-Catenin signaling
Inflammatory bowel disease (IBD) is characterized by persistent damage to the intestinal barrier and excessive inflammation, leading to increased intestinal permeability. Current treatments of IBD primarily ad...
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Article
Glial growth factor 2 treatment alleviates ischemia and reperfusion-damaged integrity of the blood-brain barrier through decreasing Mfsd2a/caveolin-1-mediated transcellular and Pdlim5/YAP/TAZ-mediated paracellular permeability
The impairment of blood-brain barrier (BBB) integrity is the pathological basis of hemorrhage transformation and vasogenic edema following thrombolysis and endovascular therapy. There is no approved drug in th...
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Article
Association Between a Failed Prominence Eruption and the Drainage of Mass from Another Prominence
Sympathetic eruptions of solar prominences have been studied for decades, however, it is usually difficult to identify their causal links. Here, we present two failed prominence eruptions on 26 October 2022 an...
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Article
Open AccessRule-based omics mining reveals antimicrobial macrocyclic peptides against drug-resistant clinical isolates
Antimicrobial resistance remains a significant global threat, driving up mortality rates worldwide. Ribosomally synthesized and post-translationally modified peptides have emerged as a promising source of nove...
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Article
A review on graphite surface modification methods towards low carbon-containing refractories
The rapid development of iron and steel metallurgy technology has promoted the continuous innovation and iteration of carbon-containing refractories for clean steel smelting. To meet the high-quality requireme...
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Article
Isolation, identification, and tolerance analysis of yeast during the natural fermentation process of Sidamo coffee beans
Yeast, which plays a pivotal role in the brewing, food, and medical industries, exhibits a close relationship with human beings. In this study, we isolated and purified 60 yeast strains from the natural fermen...
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Article
Nonlocal Kundu–Eckhaus equation: integrability, Riemann–Hilbert approach and Cauchy problem with step-like initial data
The main purpose of this paper is to discuss the Cauchy problem of integrable nonlocal (reverse-space-time) Kundu–Eckhaus (KE) equation through the Riemann–Hilbert (RH) method. Firstly, based on the zero-curva...
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Article
Open AccessCirrhotic-extracellular matrix attenuates aPD-1 treatment response by initiating immunosuppressive neutrophil extracellular traps formation in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is closely associatedwith chronic liver diseases, particularly liver cirrhosis, which has an altered extracellular matrix (ECM) composition. The influence and its mechanism of th...
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Article
Open AccessA MRI radiomics-based model for prediction of pelvic lymph node metastasis in cervical cancer
Cervical cancer (CC) is a common malignancy of the female reproductive tract, and preoperative prediction of lymph node metastasis (LNM) is essential. This study aims to design and validate a magnetic resonanc...
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Article
Open AccessTuning ferroelectric phase transition temperature by enantiomer fraction
Tuning phase transition temperature is one of the central issues in phase transition materials. Herein, we report a case study of using enantiomer fraction engineering as a promising strategy to tune the Curie...
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Article
Open AccessDiagnostic performance of a multiplexed gastrointestinal PCR panel for identifying diarrheal pathogens in children undergoing hematopoietic stem cell transplant
Diarrhea is a common complication of hematopoietic stem cell transplantation (HSCT) and is associated with substantial morbidity, but its etiology is often unknown. Etiologies of diarrhea in this population in...
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Article
Open AccessCIP2A induces PKM2 tetramer formation and oxidative phosphorylation in non-small cell lung cancer
Tumor cells are usually considered defective in mitochondrial respiration, but human non-small cell lung cancer (NSCLC) tumor tissues are shown to have enhanced glucose oxidation relative to adjacent benign lu...
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Article
Ferritinophagy induced ferroptosis in the management of cancer
Ferroptosis, a newly form of regulated cell death (RCD), is characterized by iron dyshomeostasis and unrestricted lipid peroxidation. Emerging evidence depicts a pivotal role for ferroptosis in driving some pa...
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Article
The identification method for rock strength and joint while drilling based on cutting energy density
Rock strength and joint parameters are the basic parameters reflecting engineering rock quality. The traditional rock strength testing method requires taking cores from the surrounding rock on site and transpo...
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Article
Underwater enhancement computing of ocean HABs based on cyclic color compensation and multi-scale fusion
The clarity of algal images is crucial for solving problems such as harmful algal blooms (HABs) classification and red tide warning. However, the original underwater microscopic images of HABs often produce co...
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Article
Intravenous immunoglobulin for treatment of hospitalized COVID-19 patients: an evidence map** and meta-analysis
The clinical efficacy and safety of intravenous immunoglobulin (IVIg) treatment for COVID-19 remain controversial. This study aimed to map the current status and gaps of available evidence, and conduct a meta-...
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Article
Open AccessOrigin of the multi-phasic quenching dynamics in the BLUF domains across the species
Blue light using flavin (BLUF) photoreceptors respond to light via one of nature’s smallest photo-switching domains. Upon photo-activation, the flavin cofactor in the BLUF domain exhibits multi-phasic dynamics...
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Article
Open AccessDynamic evolution and spatial difference of public health service supply in economically developed provinces of China: typical evidence from Guangdong Province
The outbreak of the COVID-19 pandemic has drawn attention from all sectors of society to the level of public health services. This study aims to investigate the level of public health service supply in the fou...
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Chapter and Conference Paper
A Comprehensive Well Productivity Evaluation Approach and Sensitivity Analysis for a HPHT Ultra-deep Water Gas Reservoir
Well testing in ultra-deep water reservoirs is crucial for well productivity evaluation, whereas well testing time is very limited due to rig days concerns, safety and drillship well testing equipment constrai...