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Open AccessAn automated data cleaning method for Electronic Health Records by incorporating clinical knowledge
The use of Electronic Health Records (EHR) data in clinical research is incredibly increasing, but the abundancy of data resources raises the challenge of data cleaning. It can save time if the data cleaning c...
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Article
Open AccessAn ensemble-based feature selection framework to select risk factors of childhood obesity for policy decision making
The increasing prevalence of childhood obesity makes it essential to study the risk factors with a sample representative of the population covering more health topics for better preventive policies and interve...
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Article
Endurance Exercise Intervention Is Beneficial to Kidney Function in a Rat Model of Isolated Abdominal Venous Congestion: a Pilot Study
In this study, the effects of moderate intense endurance exercise on heart and kidney function and morphology were studied in a thoracic inferior vena cava constricted (IVCc) rat model of abdominal venous cong...
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Article
Exercise intervention in hospitalized heart failure patients, with emphasis on congestion-related complications: a review
The importance of physical activity has become evident since a sedentary lifestyle drives cardiovascular disease progression and is associated with increased morbidity and mortality. The favorable effects of e...
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Article
Open AccessCurrent animal models for the study of congestion in heart failure: an overview
Congestion (i.e., backward failure) is an important culprit mechanism driving disease progression in heart failure. Nevertheless, congestion remains often underappreciated and clinicians underestimate the impo...
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Article
Open AccessSoftware-guided versus nurse-directed blood glucose control in critically ill patients: the LOGIC-2 multicenter randomized controlled clinical trial
Blood glucose control in the intensive care unit (ICU) has the potential to save lives. However, maintaining blood glucose concentrations within a chosen target range is difficult in clinical practice and hold...
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Article
Open AccessExternal Validation of a risk stratification model to assist shared decision making for patients starting renal replacement therapy
Shared decision making is nowadays acknowledged as an essential step when deciding on starting renal replacement therapy. Valid risk stratification of prognosis is, besides discussing quality of life, crucial ...
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Biomarkers of Endometriosis
Endometriosis is a benign gynecological disease defined by the ectopic presence of endometrium and associated with pelvic pain and infertility. The etiology and pathogenesis remain unclear. The gold standard o...
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Reference Work Entry In depth
Diuretics
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Article
Open AccessErratum to: TRIzol treatment of secretory phase endometrium allows combined proteomic and mRNA microarray analysis of the same sample in women with and without endometriosis
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Article
Open AccessTRIzol treatment of secretory phase endometrium allows combined proteomic and mRNA microarray analysis of the same sample in women with and without endometriosis
According to mRNA microarray, proteomics and other studies, biological abnormalities of eutopic endometrium (EM) are involved in the pathogenesis of endometriosis, but the relationship between mRNA and protein...
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Article
Ingredients for adequate evaluation of blood glucose algorithms as applied to the critically ill
The article by Eslami and colleagues provides an overview of the indicators used to measure the quality of blood glucose control in patients admitted to the intensive care unit. Each indicator can be related t...
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Article
Open AccessGlycemic penalty index for adequately assessing and comparing different blood glucose control algorithms
Blood glucose (BG) control performed by intensive care unit (ICU) nurses is becoming standard practice for critically ill patients. New (semi-automated) 'BG control' algorithms (or 'insulin titration' algorith...
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Article
Microarray screening for target genes of the proto-oncogene PLAG1
PLAG1 is a proto-oncogene whose ectopic expression can trigger the development of pleomorphic adenomas of the salivary glands and of lipoblastomas. As PLAG1 is a transcription factor, able to activate transcri...