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  1. Article

    Open Access

    Stromal Hedgehog pathway activation by IHH suppresses lung adenocarcinoma growth and metastasis by limiting reactive oxygen species

    Activation of the Hedgehog (Hh) signaling pathway by mutations within its components drives the growth of several cancers. However, the role of Hh pathway activation in lung cancers has been controversial. Her...

    Sahba Kasiri, Baozhi Chen, Alexandra N. Wilson, Annika Reczek… in Oncogene (2020)

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    Article

    N-Acetyl Serotonin Protects Neural Progenitor Cells Against Oxidative Stress-Induced Apoptosis and Improves Neurogenesis in Adult Mouse Hippocampus Following Traumatic Brain Injury

    In this study, with primary mouse neural progenitor cells (NPCs), we investigated the neuroprotective effect of a tropomyosin-related kinase receptor B (TrkB) agonist, N-acetyl serotonin (NAS), against hydroge...

    Qingzhi Li, Pengcheng Wang, Chuixue Huang, Baozhi Chen… in Journal of Molecular Neuroscience (2019)

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    Article

    Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

    Baozhi Chen, Michael E Dodge, Wei Tang, Jianming Lu, Zhiqiang Ma… in Nature Chemical Biology (2009)