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Article

Insulin-activated store-operated Ca²⁺ entry via Orai1 induces podocyte actin remodeling and causes proteinuria

Podocyte, the gatekeeper of the glomerular filtration barrier, is a primary target for growth factor and Ca²⁺ signaling whose perturbation leads to proteinuria. However, the effects of insulin action on store-ope...

Ji-Hee Kim, Kyu-Hee Hwang, Bao T. N. Dang, Minseob Eom… in Nature Communications (2021)