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    Variants in Apaf-1 segregating with major depression promote apoptosome function

    APAF1, encoding the protein apoptosis protease activating factor 1 (Apaf-1), has recently been established as a chromosome 12 gene conferring predisposition to major depression in humans. The molecular phenotypes...

    J Harlan, Y Chen, E Gubbins, R Mueller, J-M Roch, K Walter, M Lake… in Molecular Psychiatry (2006)