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  1. No Access

    Article

    Proteomic Profiling in the Brain of CLN1 Disease Model Reveals Affected Functional Modules

    Neuronal ceroid lipofuscinoses (NCL) are the most commonly inherited progressive encephalopathies of childhood. Pathologically, they are characterized by endolysosomal storage with different ultrastructural fe...

    Saara Tikka, Evanthia Monogioudi, Athanasios Gotsopoulos… in NeuroMolecular Medicine (2016)

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    Protocol

    MALDI-Imaging Mass Spectrometry on Tissues

    Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF)—profiling and imaging mass spectrometry (MSI) are promising technologies for measuring hundreds of different molecules directly on tissues...

    Veronica Mainini, Maciej Lalowski, Athanasios Gotsopoulos… in Clinical Proteomics (2015)