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  1. Article

    Open Access

    The human complement inhibitor Sushi Domain-Containing Protein 4 (SUSD4) expression in tumor cells and infiltrating T cells is associated with better prognosis of breast cancer patients

    The human Sushi Domain-Containing Protein 4 (SUSD4) was recently shown to function as a novel inhibitor of the complement system, but its role in tumor progression is unknown.

    Emelie Englund, Bart Reitsma, Ben C. King, Astrid Escudero-Esparza in BMC Cancer (2015)

  2. Article

    Open Access

    Claudin-5 is involved in breast cancer cell motility through the N-WASP and ROCK signalling pathways

    Recent studies have shown dysregulation in TJ structure of several cancers including breast. Claudin-5 is a protein member of the TJ structure expressed in both endothelial and epithelial cells. This study exa...

    Astrid Escudero-Esparza, Wen G Jiang in Journal of Experimental & Clinical Cancer … (2012)

  3. No Access

    Article

    Claudin-5 participates in the regulation of endothelial cell motility

    A key step in metastasis is the interaction and penetration of the vascular endothelium by cancer cells. Tight Junctions (TJ) are located between the cancer epithelial cells and between the endothelial cells f...

    Astrid Escudero-Esparza, Wen G. Jiang in Molecular and Cellular Biochemistry (2012)