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Open AccessNeuropilin-1 and placental growth factor as prognostic factors in metastatic breast cancer
Angiogenesis is crucial for tumor development, progression, and metastasizing. The most important regulator of angiogenesis is the vascular endothelial growth factor (VEGF) family, which is involved in multipl...
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Open AccessHigh baseline Tie1 level predicts poor survival in metastatic breast cancer
Angiopoietin growth factors (Angs) regulate angiogenesis and lymphangiogenesis by binding to the endothelial Tie2 receptor. Ang2 expression is elevated in tissue hypoxia and inflammation, which also induce cle...