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  1. Article

    Open Access

    Bcr-Abl tyrosine kinase inhibitors- current status

    Bcr-Abl plays a central role in the development of chromosome positive leukaemia. Chronic Myeloid leukaemia occurs due to increase proliferation and resistance to apoptosis by Bcr-Abl positive cells. Imatinib ...

    Anum Mughal, Hafiz Muhammad Aslam, Aga Muhammad Hammad Khan in Infectious Agents and Cancer (2013)

  2. Article

    Open Access

    c-Met inhibitors

    c-Met is a receptor tyrosine kinase that encodes protein such as hepatocyte growth factor receptor (HGFR). Inappropriate activity of c-Met can cause wide variety of carcinomas. c-Met inhibitor are relatively n...

    Anum Mughal, Hafiz Muhammad Aslam, Asfandyar Sheikh in Infectious Agents and Cancer (2013)