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  1. Article

    Open Access

    Efficacy of amoxicillin/clavulanic acid after surgical drainage of perianal abscess in the prevention of the development of anal fistula (PERIQxA study): study protocol for a multicenter randomized, double-blind clinical trial

    Anorectal fistula, which is a relatively common pathology, is the chronic manifestation of the acute perirectal process that forms an anal abscess. The development of a fistula after incision and drainage of a...

    Verónica Polaino Moreno, Antonio F. Caballero-Bermejo, Mariano Artés Caselles in Trials (2024)

  2. Article

    Open Access

    Sarilumab versus standard of care for the early treatment of COVID-19 pneumonia in hospitalized patients: SARTRE: a structured summary of a study protocol for a randomised controlled trial

    In some patients, acute, life-threatening respiratory injury produced by viruses such as SARS-CoV and other viral pneumonia are associated with an over-exuberant cytokine release. Elevated levels of blood IL-6...

    Antonio F. Caballero Bermejo, Belén Ruiz-Antorán, Ana Fernández Cruz in Trials (2020)