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    Article

    The mammalian mismatch repair protein MSH2 is required for correct MRE11 and RAD51 relocalization and for efficient cell cycle arrest induced by ionizing radiation in G2 phase

    In yeast, MSH2 plays an important role in mismatch repair (MMR) and recombination, whereas the function of the mammalian MSH2 protein in recombinational repair is not completely established. We examined the ce...

    Annapaola Franchitto, Pietro Pichierri, Rita Piergentili, Marco Crescenzi… in Oncogene (2003)

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    Article

    Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle

    Werner's syndrome (WS) is an autosomal recessive disorder, characterized at the cellular level by genomic instability in the form of variegated translocation mosaicism and extensive deletions. Individuals with...

    Pietro Pichierri, Filippo Rosselli, Annapaola Franchitto in Oncogene (2003)