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Article
Open AccessIntracellular cartilage oligomeric matrix protein augments breast cancer resistance to chemotherapy
Chemotherapy persists as the primary intervention for breast cancer, with chemoresistance posing the principal obstacle to successful treatment. Herein, we show that cartilage oligomeric matrix protein (COMP) ...
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Article
Open AccessAlternative translation and retrotranslocation of cytosolic C3 that detects cytoinvasive bacteria
Complement C3 was originally regarded as a serum effector protein, although recent data has emerged suggesting that intracellular C3 can also regulate basic cellular processes. Despite the growing interest in ...
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Article
Plasma bikunin: Half-life and tissue uptake
Bikunin is a chondroitin sulfate-containing plasma protein synthesized in the liver. In vitro, it has been shown to inhibit proteases and to have additional activities, but its biological function is still unclea...