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ECU too
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Preventing the Spread of Meningococcal Infection
Meningococcal disease is a much-feared infectious disease with high mortality, unpredictable epidemiology and a predilection for the young. Primary prevention by vaccination cannot yet be fully achieved, so co...
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Taking exception
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Coupling of agonist binding to channel gating in the GABAA receptor
Neurotransmitters such as acetylcholine and GABA (γ-aminobutyric acid) mediate rapid synaptic transmission by activating receptors belonging to the gene superfamily of ligand-gated ion channels (LGICs)1. These ch...
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Open AccessBorrelia burgdorferi sensu lato in Ixodes ricinus ticks from Norway: evaluation of a PCR test targeting the chromosomal flaB gene
A consensus TaqMan real-time PCR test targeting the chromosomal flaB gene of Borrelia burgdorferi sensu lato was constructed. The test was compared with a recently published generic Light Upon eXtension (LUX) 16S...
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Open AccessMultilocus sequence ty** and ftsI sequencing: a powerful tool for surveillance of penicillin-binding protein 3-mediated beta-lactam resistance in nontypeable Haemophilus influenzae
Beta-lactam resistance in Haemophilus influenzae due to ftsI mutations causing altered penicillin-binding protein 3 (PBP3) is increasing worldwide. Low-level resistant isolates with the N526K substitution (group ...
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Open AccessHigh levels of multiresistance in quinolone resistant urinary tract isolates of Escherichia coli from Norway; a non clonal phenomen?
The problem of emerging ciprofloxacin resistance is compounded by its frequent association with multiresistance, the reason for which is not fully understood. In this study we compare multiresistance, clonal s...
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Pathways from adult education to well-being: The Tuijnman model revisited
There is a growing interest among researchers and policy-makers in the influence of adult learning on a range of outcomes, notably health and well-being. Much of the research to date has tended to focus on you...
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Open AccessDetection of Anaplasma phagocytophilum in Ixodes ricinus ticks from Norway using a realtime PCR assay targeting the Anaplasma citrate synthase gene gltA
A TaqMan real-time PCR assay targeting the Anaplasma citrate synthase gene, gltA, was developed and used for detection of Anaplasma phagocytophilum in 765 Ixodes ricinus ticks collected from dogs and cats in nort...
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Open AccessDevelopment and evaluation of 16 new microsatellite loci for the rock ptarmigan (Lagopus muta) and cross-species amplification for the willow grouse (L. lagopus)
The genetic markers designed for this study can facilitate future genetic studies on the rock ptarmigan (Lagopus muta). To our knowledge no microsatellite markers have ever been developed specifically for this sp...
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Open AccessModulating native GABAA receptors in medulloblastoma with positive allosteric benzodiazepine-derivatives induces cell death
Pediatric brain cancer medulloblastoma (MB) standard-of-care results in numerous comorbidities. MB is comprised of distinct molecular subgroups. Group 3 molecular subgroup patients have the highest relapse rat...
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Demonstration of a Trauma-Informed Assessment to Intervention Model in a Large Urban School District
This manuscript describes an implementation of a new model for integrated school mental health services. By incorporating trauma-informed practices with universal screening and teacher coaching, this study exa...
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Open AccessDetection of Candidatus Neoehrlichia mikurensis in Norway up to the northern limit of Ixodes ricinus distribution using a novel real time PCR test targeting the groEL gene
Candidatus Neoehrlichia mikurensis is an emerging tick-borne pathogen. It is widely distributed in Ixodes ricinus ticks in Europe, but knowledge of its distribution in Norway, where I. ricinus reaches its norther...
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Open AccessCorrection to: Detection of Candidatus Neoehrlichia mikurensis in Norway up to the northern limit of Ixodes ricinus distribution using a novel real time PCR test targeting the groEL gene
After publication of our article [1] it came to our notice that the source of the sequence for the control plasmid, pNeo (Materials and methods: Controls) was incorrectly stated as AB094461. The correct access...
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Open AccessA nature-based solution to a landfill-leachate contamination of a confined aquifer
Remediation of groundwater from landfill contamination presents a serious challenge due to the complex mixture of contaminants discharged from landfills. Here, we show the significance of a nature-based soluti...
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Profiles of Rater Dis/Agreement within Universal Screening in Predicting Distal Outcomes
The success of a comprehensive and integrated school mental health system is dependent on data to inform decision-making. Universal screening is one such method utilized by schools to inform treatment across u...
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Open AccessMicrobial assembly and co-occurrence network in an aquifer under press perturbation
Thousands of aquifers worldwide have been polluted by leachate from landfills and many more remained threatened. Microbial communities from these environments play a crucial role in mediating biodegradation an...
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Pulmonary hypertension is associated with poor cardiovascular and hematologic outcomes in patients with myeloproliferative neoplasms and cardiovascular disease
Cardiovascular events and hematologic progression to myelofibrosis or leukemia are leading causes of morbidity and mortality among patients with myeloproliferative neoplasms (MPN). Pulmonary hypertension (PH) ...
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Open AccessDietary counselling plus omega-3 supplementation in the treatment of generalized anxiety disorder: protocol for a randomized wait-list controlled pilot trial (the “EASe-GAD Trial”)
Anxiety disorders are prevalent and disabling conditions involving excessive worry and tension. Generalized anxiety disorder (GAD), the most common anxiety disorder, affects 5% of individuals from high-income ...
