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Article
De novo mutations identified by exome sequencing implicate rare missense variants in SLC6A1 in schizophrenia
Schizophrenia is a highly polygenic disorder with important contributions from both common and rare risk alleles. We analyzed exome sequencing data for de novo variants (DNVs) in a new sample of 613 schizophre...
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Article
Evolutionary expansion and anatomical specialization of synapse proteome complexity
Grant and colleagues used comparative proteomics and genomics to examine the evolution of the postsynaptic density and MAGUK-associated signaling complexes implicated in learning and memory. They found conserv...