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De novo mutations identified by exome sequencing implicate rare missense variants in SLC6A1 in schizophrenia

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  1. Article

    Open Access

    Genetic association of FMRP targets with psychiatric disorders

    Genes encoding the mRNA targets of fragile X mental retardation protein (FMRP) are enriched for genetic association with psychiatric disorders. However, many FMRP targets possess functions that are themselves ...

    Nicholas E. Clifton, Elliott Rees, Peter A. Holmans in Molecular Psychiatry (2021)

  2. Article

    Open Access

    Polygenic risk for schizophrenia and subcortical brain anatomy in the UK Biobank cohort

    Research has shown differences in subcortical brain volumes between participants with schizophrenia and healthy controls. However, none of these differences have been found to associate with schizophrenia poly...

    Steluta Grama, Isabella Willcocks, John J. Hubert in Translational Psychiatry (2020)

  3. Article

    Open Access

    Dynamic expression of genes associated with schizophrenia and bipolar disorder across development

    Common genetic variation contributes a substantial proportion of risk for both schizophrenia and bipolar disorder. Furthermore, there is evidence of significant, but not complete, overlap in genetic risk betwe...

    Nicholas E. Clifton, Eilís Hannon, Janet C. Harwood in Translational Psychiatry (2019)