5 Result(s)
within
Andrew Hall
Life Sciences
English
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Article
Open AccessComputational approaches identify a transcriptomic fingerprint of drug-induced structural cardiotoxicity
Structural cardiotoxicity (SCT) presents a high-impact risk that is poorly tolerated in drug discovery unless significant benefit is anticipated. Therefore, we aimed to improve the mechanistic understanding of...
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Article
Open AccessThe endogenous subcellular localisations of the long chain fatty acid-activating enzymes ACSL3 and ACSL4 in sarcoma and breast cancer cells
Fatty acid uptake and metabolism are often dysregulated in cancer cells. Fatty acid activation is a critical step that allows these biomolecules to enter cellular metabolic pathways such as mitochondrial β-oxi...
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Article
Open AccessWhy do many pheasants released in the UK die, and how can we best reduce their natural mortality?
Around 60% of pheasants released for shooting in the UK, an estimated 21 million birds, do not end up at their intended fate: being shot. This constitutes wastage, raising economic, environmental and ethical q...
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Article
Female-biased dispersal in a spatially restricted endemic island bird
Dispersal of individuals before their first breeding attempt or between subsequent attempts facilitates spatial and temporal gene flow within and among populations. However, in species on oceanic islands, disp...
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Article
Within-season temporal variation in correlations between vineyard canopy and winegrape composition and yield
Remote optical imaging can rapidly acquire information describing spatial variability in vineyard block performance. Canopy characteristics were derived from very high spatial resolution (0.25 m) optical image...
