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Article
Open AccessMmCMS: mouse models’ consensus molecular subtypes of colorectal cancer
Colorectal cancer (CRC) primary tumours are molecularly classified into four consensus molecular subtypes (CMS1–4). Genetically engineered mouse models aim to faithfully mimic the complexity of human cancers a...
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Article
Open AccessMelanoma tumor growth is accelerated in a mouse model of sickle cell disease
The effect of sickle cell disease (SCD) on tumor growth is unknown. Sickled red blood cells may form aggregates within the microvasculature of hypoxic tumors and reduce blood flow leading to impairment of tumo...
