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within Andrei Kucharavy Remove this filter Science, Humanities and Social Sciences, multidisciplinary Remove this filter

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    Article

    Hypo-osmotic-like stress underlies general cellular defects of aneuploidy

    Aneuploidy, which refers to unbalanced chromosome numbers, represents a class of genetic variation that is associated with cancer, birth defects and eukaryotic micro-organisms1–4. Whereas it is known that each an...

    Hung-Ji Tsai, Anjali R. Nelliat, Mohammad Ikbal Choudhury, Andrei Kucharavy… in Nature (2019)

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    Article

    Cytosolic proteostasis through importing of misfolded proteins into mitochondria

    Proteins prone to aggregation in yeast are imported into mitochondria under stress conditions, suggesting that mitochondrial import and proteolysis may help to disaggregate proteins in the cytoplasm.

    Linhao Ruan, Chuankai Zhou, Erli **, Andrei Kucharavy, Ying Zhang, Zhihui Wen… in Nature (2017)