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  1. No Access

    Article

    A microbiome-dependent gut–brain pathway regulates motivation for exercise

    Exercise exerts a wide range of beneficial effects for healthy physiology1. However, the mechanisms regulating an individual’s motivation to engage in physical activity remain incompletely understood. An importan...

    Lenka Dohnalová, Patrick Lundgren, Jamie R. E. Carty, Nitsan Goldstein… in Nature (2022)

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    Article

    β-Hydroxybutyrate suppresses colorectal cancer

    Colorectal cancer (CRC) is among the most frequent forms of cancer, and new strategies for its prevention and therapy are urgently needed1. Here we identify a metabolite signalling pathway that provides actionabl...

    Oxana Dmitrieva-Posocco, Andrea C. Wong, Patrick Lundgren, Aleksandra M. Golos… in Nature (2022)

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    Chapter

    Intrathecal Drug Delivery: Medication Selection

    The appropriate selection of medications is key to the accomplishment of symptom control when using an intrathecal drug delivery system (IDDS). Medications must be preservative-free, safe for intrathecal use, ...

    Andrea C. Wong, Salim M. Hayek in Advanced Procedures for Pain Management (2018)