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  1. Article

    Open Access

    Determining clinical course of diffuse large B-cell lymphoma using targeted transcriptome and machine learning algorithms

    Multiple studies have demonstrated that diffuse large B-cell lymphoma (DLBCL) can be divided into subgroups based on their biology; however, these biological subgroups overlap clinically. Using machine learnin...

    Maher Albitar, Hong Zhang, Andre Goy, Zijun Y. Xu-Monette in Blood Cancer Journal (2022)

  2. No Access

    Article

    Systemic Exposure of Rituximab Increased by Ibrutinib: Pharmacokinetic Results and Modeling Based on the HELIOS Trial

    In the HELIOS trial, bendamustine/rituximab (BR) plus ibrutinib (BR-I) improved disease outcomes versus BR plus placebo in previously treated chronic lymphocytic leukemia/small lymphocytic lymphoma. Here, we desc...

    Silvia Maria Lavezzi, Jan de Jong, Martine Neyens, Paula Cramer in Pharmaceutical Research (2019)

  3. No Access

    Article

    Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma

    Clinical testing of BCR inhibition on DLBCL reveals determinants of response.

    Wyndham H Wilson, Ryan M Young, Roland Schmitz, Yandan Yang in Nature Medicine (2015)