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  1. No Access

    Article

    An intrinsic role of IL-33 in Treg cell–mediated tumor immunoevasion

    Regulatory T (Treg) cells accumulate into tumors, hindering the success of cancer immunotherapy. Yet, therapeutic targeting of Treg cells shows limited efficacy or leads to autoimmunity. The molecular mechanisms ...

    Aikaterini Hatzioannou, Aggelos Banos, Theodore Sakelaropoulos… in Nature Immunology (2020)

  2. No Access

    Article

    Subset-specific alterations in frequencies and functional signatures of γδ T cells in systemic sclerosis patients

    Here, we evaluated the distribution and functional profile of circulating CD27+ and CD27− γδ T-cell subsets in systemic sclerosis (SSc) patients to assess their potential role in this disorder.

    Ana Henriques, Cláudia Silva, Mariana Santiago… in Inflammation Research (2016)

  3. Article

    Open Access

    Sera from patients with active systemic lupus erythematosus patients enhance the toll-like receptor 4 response in monocyte subsets

    Systemic Lupus Erythematosus (SLE) is an auto-immune disease whose complex pathogenesis remains unraveled. Here we aim to explore the inflammatory ability of SLE patients’ sera upon peripheral blood (PB) monoc...

    Tiago Carvalheiro, Diane Gomes, Ligia A. Pinto, Luis Inês… in Journal of Inflammation (2015)

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  4. No Access

    Article

    Alterations on peripheral blood B cell subsets induced by allergic rhinitis

    Here we evaluated whether allergic rhinitis to Dermatophagoides pteronyssinus induces alterations on circulating B cell subsets.

    Ana Henriques, Rodrigo Nunes, Graça Loureiro, António Martinho… in Inflammation Research (2015)