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Article
Expression of the Wnt antagonist DKK3 is frequently suppressed in sporadic epithelial ovarian cancer
The Wnt pathway plays an important role in embryonic development, and defects in this pathway have been implicated in the tumorigenesis. The Dickkopf 3 (DKK3) is a putative Wnt signaling inhibitor that is freq...
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Article
Open AccessSiah1 proteins enhance radiosensitivity of human breast cancer cells
Siah proteins play an important role in cancer progression. We evaluated the effect of Siah1, its splice variants Siah1L and the Siah1 mutant with the RING finger deleted (Siah1ΔR) on radiosensitization of hum...
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Article
Open AccessIncreased expression of EphA7 correlates with adverse outcome in primary and recurrent glioblastoma multiforme patients
Malignant gliomas are lethal cancers, highly dependent on angiogenesis and treatment options and prognosis still remain poor for patients with recurrent glioblastoma multiforme (GBM). Ephs and ephrins have man...