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Article
Genome-wide Kdm4 histone demethylase transcriptional regulation in Drosophila
The histone lysine demethylase 4 (Kdm4/Jmjd2/Jhdm3) family is highly conserved across species and reverses di- and tri-methylation of histone H3 lysine 9 (H3K9) and lysine 36 (H3K36) at the N-terminal tail of ...
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Article
Open AccessCanonical and non-canonical JAK/STAT transcriptional targets may be involved in distinct and overlap** cellular processes
The Janus kinase-signal transducer and activator of transcription (JAK/STAT) pathway has been well-characterized as a crucial signal transduction cascade that regulates vital biological responses including dev...
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Article
A quorum-sensing signal promotes host tolerance training through HDAC1-mediated epigenetic reprogramming
The mechanisms by which pathogens evade elimination without affecting host fitness are not well understood. For the pathogen Pseudomonas aeruginosa, this evasion appears to be triggered by excretion of the quorum...