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  1. No Access

    Article

    A distinct abundant group of microbial rhodopsins discovered using functional metagenomics

    Many organisms capture or sense sunlight using rhodopsin pigments1,2, which are integral membrane proteins that bind retinal chromophores. Rhodopsins comprise two distinct protein families 1 ...

    Alina Pushkarev, Keiichi Inoue, Shirley Larom, José Flores-Uribe, Manish Singh… in Nature (2018)

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    Article

    Crystal structure of heliorhodopsin

    Heliorhodopsins (HeRs) are a family of rhodopsins that was recently discovered using functional metagenomics1. They are widely present in bacteria, archaea, algae and algal viruses2,3. Although HeRs have seven pr...

    Wataru Shihoya, Keiichi Inoue, Manish Singh, Masae Konno, Shoko Hososhima… in Nature (2019)

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    Protocol

    Searching Metagenomes for New Rhodopsins

    Most microbial groups have not been cultivated yet, and the only way to approach the enormous diversity of rhodopsins that they contain in a sensible timeframe is through the analysis of their genomes. High-th...

    Francisco Rodriguez-Valera, Alina Pushkarev, Riccardo Rosselli, Oded Béjà in Rhodopsin (2022)

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    Article

    Phototrophy by antenna-containing rhodopsin pumps in aquatic environments

    Energy transfer from light-harvesting ketocarotenoids to the light-driven proton pump xanthorhodopsins has been previously demonstrated in two unique cases: an extreme halophilic bacterium1 and a terrestrial cyan...

    Ariel Chazan, Ishita Das, Takayoshi Fujiwara, Shunya Murakoshi, Andrey Rozenberg… in Nature (2023)