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    Article

    PPARγ agonists: potential treatment for autism spectrum disorder by inhibiting the canonical WNT/β-catenin pathway

    Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is characterized by a deficit in social interactions and communication with repetitive and restrictive behavior. No curative treatments are ...

    Alexandre Vallée, Jean-Noël Vallée, Yves Lecarpentier in Molecular Psychiatry (2019)

  2. Article

    Open Access

    The influence of circadian rhythms and aerobic glycolysis in autism spectrum disorder

    Intellectual abilities and their clinical presentations are extremely heterogeneous in autism spectrum disorder (ASD). The main causes of ASD remain unclear. ASD is frequently associated with sleep disorders. ...

    Alexandre Vallée, Yves Lecarpentier, Rémy Guillevin in Translational Psychiatry (2020)

  3. Article

    Open Access

    Lithium: a potential therapeutic strategy in obsessive–compulsive disorder by targeting the canonical WNT/β pathway

    Obsessive–compulsive disorder (OCD) is a neuropsychiatric disorder characterized b–y recurrent and distinctive obsessions and/or compulsions. The etiologies remain unclear. Recent findings have shown that oxid...

    Alexandre Vallée, Jean-Noël Vallée, Yves Lecarpentier in Translational Psychiatry (2021)

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    Article

    Possible actions of cannabidiol in obsessive-compulsive disorder by targeting the WNT/β-catenin pathway

    Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder characterized by recurrent and distinctive obsessions and/or compulsions. The etiologies remain unclear. Recent findings have shown that oxida...

    Alexandre Vallée, Yves Lecarpentier, Jean-Noël Vallée in Molecular Psychiatry (2022)