Skip to main content

3 Result(s)

within Aizhen **ong Remove this filter Biomedicine Remove this filter

and

  1. No Access

    Article

    Functional metabolomics characterizes the contribution of farnesoid X receptor in pyrrolizidine alkaloid-induced hepatic sinusoidal obstruction syndrome

    Consumption of herbal products containing pyrrolizidine alkaloids (PAs) is one of the major causes for hepatic sinusoidal obstruction syndrome (HSOS), a deadly liver disease. However, the crucial metabolic var...

    Aizhen **ong, Longhui Lu, Kaiyuan Jiang, **aoning Wang, Yan Chen… in Archives of Toxicology (2024)

  2. Article

    Open Access

    A TMT-based shotgun proteomics uncovers overexpression of thrombospondin 1 as a contributor in pyrrolizidine alkaloid-induced hepatic sinusoidal obstruction syndrome

    Hepatic sinusoidal obstruction disease (HSOS) is a rare but life-threatening vascular liver disease. However, its underlying mechanism and molecular changes in HSOS are largely unknown, thus greatly hindering ...

    Weiqian Wang, Yan Chen, Yue Yin, Xunjiang Wang, Xuanling Ye… in Archives of Toxicology (2022)

    Download PDF (2049 KB) View Article

  3. No Access

    Article

    Evaluation of a Potential Clinical Significant Drug-Drug Interaction between Digoxin and Bupropion in Cynomolgus Monkeys

    A three-period digoxin-bupropion drug-drug interaction study was performed in cynomolgus monkeys to assess the effect of bupropion and its metabolites on digoxin disposition.

    Yang Shen, Yang Yu, Wei Lai, Shuai Li, Zixuan Xu, Jie**g **… in Pharmaceutical Research (2018)