Page
%P
-
Article
Curcumin induces apoptosis through mitochondrial pathway and caspases activation in human melanoma cells
Melanoma is the most malignant skin cancer and is highly resistant to chemotherapy and radiotherapy. Curcumin is a component of turmeric, the yellow spice derived from the rhizome of Curcuma longa. It has been de...
-
Article
Progression of O6-methylguanine-DNA methyltransferase and temozolomide resistance in cancer research
Temozolomide (TMZ) is an alkylating agent that is widely used in chemotherapy for cancer. A key mechanism of resistance to TMZ is the overexpression of O6-methylguanine-DNA methyltransferase (MGMT). MGMT specific...