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within Adrienn Volak Remove this filter Science, Humanities and Social Sciences, multidisciplinary Remove this filter

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  1. Article

    Open Access

    In vivo engineering of lymphocytes after systemic exosome-associated AAV delivery

    Ex-vivo gene therapy using stem cells or T cells transduced by retroviral or lentiviral vectors has shown remarkable efficacy in the treatment of immunodeficiencies and cancer. However, the process is expensive, ...

    Cort B. Breuer, Killian S. Hanlon, Jeya-shree Natasan, Adrienn Volak… in Scientific Reports (2020)

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  2. Article

    Open Access

    High levels of AAV vector integration into CRISPR-induced DNA breaks

    Adeno-associated virus (AAV) vectors have shown promising results in preclinical models, but the genomic consequences of transduction with AAV vectors encoding CRISPR-Cas nucleases is still being examined. In ...

    Killian S. Hanlon, Benjamin P. Kleinstiver, Sara P. Garcia… in Nature Communications (2019)

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