17 Result(s)
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Article
Intensive chemotherapy followed by autologous stem cell transplantation in primary central nervous system lymphomas (PCNSLs). Therapeutic outcomes in real life—experience of the French Network
We analysed the therapeutic outcomes of all consecutive patients with primary central nervous system lymphoma (PCNSL) registered in the prospective French database for PCNSL and treated with intensive chemothe...
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Complement System: a Neglected Pathway in Immunotherapy
Approved for the treatment of autoimmune diseases, hematological malignancies, and solid cancers, several monoclonal antibodies (mAb) make use of complement in their mechanism of action. Such an assessment is ...
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Article
Open AccessA simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial
Patients with multiple myeloma are generally older and vary in fitness levels, which may influence the clinical benefit of treatment. Patients from the large, phase 3 FIRST trial in newly diagnosed multiple my...
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Article
Open AccessSTIM1 at the plasma membrane as a new target in progressive chronic lymphocytic leukemia
Dysregulation in calcium (Ca2+) signaling is a hallmark of chronic lymphocytic leukemia (CLL). While the role of the B cell receptor (BCR) Ca2+ pathway has been associated with disease progression, the importance...
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Article
Open Access17p deletion strongly influences rituximab elimination in chronic lymphocytic leukemia
Chronic lymphocytic leukemia (CLL) is the most common type of leukemia and the anti-CD20 monoclonal antibody, rituximab, represents the therapeutic gold standard for more than 2 decades in this pathology, when...
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Article
Isolated Cardiac Richter Syndrome: a Case Report
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Article
Late relapsing mantle cell lymphoma showing preserved sensitivity to single-agent lenalidomide
Mantle cell lymphoma is a hematologic malignancy characterized by poor therapeutic outcomes. Immunomodulatory drugs are a focus of attention in this disease, especially for the elderly and frail patients not a...
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Identification of patients with indolent B cell lymphoma sensitive to rituximab monotherapy
The potential predictive value of tumor bulk, genetic, and immunological variants in patients with low-grade non-Hodgkin's lymphoma to respond to treatment with rituximab (RTX) monotherapy was evaluated. Thus,...
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Infection by H1N1 flu virus revealing T-cell acute lymphoid leukaemia: about two cases
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Combined therapy associating systemic platinum-based chemotherapy and local radiotherapy into the treatment of primary intraocular lymphoma
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Open AccessAcute dyspnoea and single tracheal localisation of mantle cell lymphoma
Mantle cell lymphoma is a lymphoid entity characterized by adenopathy, blood and bone marrow involment which only recurrent mucosal localisation is the lymphomatoid polyposis. Few other mucosal infiltrations h...
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Article
18F-FDG PET/CT in primary non-Hodgkin's lymphoma of the sinonasal tract
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Article
Peripheral blood stem cell collection in elderly patients
Intensive treatments like autologous blood stem cell transplantations are standard consolidation treatments for lymphoma and myeloma in young people. The upper age limit for these procedures is constantly incr...
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Lenalidomide, as a single agent, induces complete remission in a refractory mantle cell lymphoma
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Tri-lineage disease involving sideroblastic anaemia, multiple myeloma and B-cell non-Hodgkin’s lymphoma in the same patient
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A combination therapy with fludarabine, mitoxantrone and rituximab induces complete immunophenotypical remission in B-cell prolymphocytic leukaemia
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High-dose melphalan followed by a second bone marrow transplantation in early relapse of acute myeloid leukemia after bone marrow transplantation in children
