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  1. Article

    Open Access

    Reduced gut microbiome protects from alcohol-induced neuroinflammation and alters intestinal and brain inflammasome expression

    The end-organ effects of alcohol span throughout the entire body, from the gastrointestinal tract to the central nervous system (CNS). In the intestine, alcohol use changes the microbiome composition and incre...

    Patrick P. Lowe, Benedek Gyongyosi, Abhishek Satishchandran in Journal of Neuroinflammation (2018)

  2. Article

    Open Access

    Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations

    Chronic alcohol consumption is associated with neuroinflammation, neuronal damage, and behavioral alterations including addiction. Alcohol-induced neuroinflammation is characterized by increased expression of ...

    Patrick P. Lowe, Caroline Morel, Aditya Ambade in Journal of Neuroinflammation (2020)