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  1. No Access

    Article

    Genome-wide identification and annotation of SNPs for economically important traits in Frieswal™, newly evolved crossbred cattle of India

    The Frieswal™ is a crossbred cattle evolved by ICAR-Central Institute for Research on Cattle utilizing more than 15,000 cattle maintained at more than 37 military farms spread all over the agro-climatic region...

    Thiruvothur Venkatesan Raja, Rani Alex, Umesh Singh, Sushil Kumar… in 3 Biotech (2023)

  2. Article

    Seasonal Variations in Bioaccumulation and Translocation of Toxic Heavy Metals in the Dominant Vegetables of East Kolkata Wetlands: a Case Study with Suggestive Ecorestorative Strategies

    In recent times, East Kolkata Wetlands (EKW), a designated Ramsar site in the eastern part of megacity Kolkata, has been threatened by toxic heavy metal (HM) pollution. Besides being a natural wetland supporti...

    Sangita Agarwal, Pritam Mukherjee… in Applied Biochemistry and Biotechnology (2023)

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    Article

    Effects of point mutations on the thermostability of B. subtilis lipase: investigating nonadditivity

    Molecular level understanding of mutational effects on stability and activity of enzymes is challenging particularly when several point mutations are incorporated during the directed evolution experiments. In ...

    Bipin Singh, Gopalakrishnan Bulusu… in Journal of Computer-Aided Molecular Design (2016)

  4. No Access

    Article

    Small Interfering RNA (siRNA)-Mediated Knockdown of Myostatin Influences the Expression of Myogenic Regulatory Factors in Caprine Foetal Myoblasts

    Myostatin (MSTN) acts as a negative regulator of skeletal muscle development. Naturally occurring inactivating mutations in the coding region and knockout as well as knockdown of MSTN result in an increase in the...

    Rohit Kumar, Satyendra Pal Singh, Priya Kumari… in Applied Biochemistry and Biotechnology (2014)

  5. No Access

    Article

    Modeling the noncovalent interactions at the metabolite binding site in purine riboswitches

    We present gas phase quantum chemical studies on the metabolite binding interactions in two important purine riboswitches, the adenine and guanine riboswitches, at the B3LYP/6-31G(d,p) level of theory. In orde...

    Purshotam Sharma, Sitansh Sharma, Mohit Chawla… in Journal of Molecular Modeling (2009)

  6. No Access

    Article

    Base pairing in RNA structures: A computational analysis of structural aspects and interaction energies

    The base pairing patterns in RNA structures are more versatile and completely different as compared to DNA. We present here results of ab-initio studies of structures and interaction energies of eight selected RN...

    Purshotam Sharma, Abhijit Mitra, Sitansh Sharma… in Journal of Chemical Sciences (2007)