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3 Result(s)

within A. Riemann Remove this filter Life Sciences Remove this filter English Remove this filter Cancer Research Remove this filter Regenerative Medicine/Tissue Engineering Remove this filter

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  1. No Access

    Chapter and Conference Paper

    Evaluation of Betulinic Acid Derivatives as PET Tracers for Hypoxia-Induced Carbonic Anhydrase IX (CA IX) Expression

    Non-invasive visualisation of the expression of hypoxia-related proteins, such as carbonic anhydrase IX (CA IX), by positron emission tomography (PET) could provide important information on the oxygenation sta...

    V. Haupt, D. Gündel, E. Prell, M. Kahnt, S. Sommerwerk… in Oxygen Transport to Tissue XLIII (2022)

  2. No Access

    Chapter and Conference Paper

    Acidosis-Induced Regulation of Egr1 and Ccn1 In Vitro and in Experimental Tumours In Vivo

    Extracellular acidosis is a characteristic of solid tumours, resulting from hypoxia-induced glycolytic metabolism as well as from the “Warburg effect” (aerobic glycolysis). The acidic environment has shown to ...

    M. Rauschner, S. Reime, A. Riemann, O. Thews in Oxygen Transport to Tissue XLIII (2022)

  3. No Access

    Chapter and Conference Paper

    Role of the mTOR Signalling Pathway During Extracellular Acidosis in Tumour Cells

    The metabolic microenvironment of solid tumours is often dominated by extracellular acidosis which results from glycolytic metabolism. Acidosis can modulate gene expression and foster the malignant progression...

    M. Wolff, M. Rauschner, S. Reime, A. Riemann, O. Thews in Oxygen Transport to Tissue XLIII (2022)