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Article
Effects of different doses of apomorphine on GAD activity in rat substantia nigra
The effects of different doses of the dopamine (DA) receptor agonist apomorphine on the activity of the γ-aminobutyric acid (GABA)-synthesizing enzyme glutamic acid decarboxylase (GAD, EC 4.1.1.15) were invest...
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Article
Variations in the 5-hydroxyindoleacetic acid concentration in the cerebrospinal fluid during the sleep-wake cycle in man
A variation in the ventricular fluid 5-HIA A concentration has been observed during the phases of the sleep-wake cycle in man. This variation affects the NREM phase, during which 5-HIAA increases markedly, rat.....
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Article
IgG1,3 and 4 oligoclonal bands in multiple sclerosis and other neurological diseases
Cerebrospinal fluid (CSF)samples from 10 patients with Multiple Sclerosis (MS) and 7 with other neurological diseases (OND) were studied in order to detect oligoclonal restriction of IgG subclasses 1,3 and 4. ...
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Article
Prevalence of moderate and severe Alzheimer dementia and multi-infarct dementia in the population of southeastern Sicily
We have calculate the prevalence rates of moderate and severe dementia of the Alzheimer type (DAT) and of multi-infarct dementia (MID) in a Sicilian population sample aged 40 and over. For DAT the prevalence r...
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Article
Epidemiological survey of multiple sclerosis in Catania city
The findings of an epidemiological survey of multiple sclerosis (MS) in the urban area of Catania reveal a new and in some respects original pattern of MS cases recorded on 31 December 1989 (prevalence day).
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Article
Fourth meeting of the European Neurological Society 25–29 June 1994 Barcelona, Spain
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Article
De effecten van revalidatietherapie op de beperkingen en de functionele afhankelijkheid van patiënten met de ziekte van Parkinson
Om informatie te verkrijgen over de rol van de revalidatie in de algemene zorg bij Parkinson-patiënten werden door ons twee parallel-onderzoeken uitgevoerd naar de effecten van een vier weken durend, intensief...
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Article
Stroke incidence and survival in three Sicilian municipalities
We investigated the incidence of first-ever stroke in three Sicilian municipalities over the years 1984–1987. Case ascertainment involved two approaches: a doorto-door two-phase prevalence survey and a study o...
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Article
Deafness: an unusual onset of genetic Creutzfeldt-Jakob disease
We describe a case of genetic Creutzfeldt-Jakob disease (CJD) with deafness at the onset. We report clinical features, 14-3-3 protein positivity, electroencephalography and brain stem auditory evoked potentia...
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Article
A possible spatial and temporal cluster of multiple sclerosis in the town of Linguaglossa, Sicily
We carried out an epidemiological survey to determine prevalence and incidence of multiple sclerosis in the little town of Linguaglossa in the Province of Catania. We calculated prevalence rate as point preval...
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Article
The combination of cyclophosphamide plus interferon beta as rescue therapy could be used to treat relapsing–remitting multiple sclerosis patients
The aim of the present study was to evaluate the efficacy of the combination of cyclophosphamide (CTX) and interferon beta (IFN β) in a group of relapsing remitting (RR) multiple sclerosis (MS) patients who ex...
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Article
Open AccessOsteogenic differentiation of skeletal muscle progenitor cells is activated by the DNA damage response
Heterotopic ossification (HO) is a pathological condition characterized by the deposition of mineralized tissue in ectopic locations such as the skeletal muscle. The precise cellular origin and molecular mecha...