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Article
Über die Sekretionsgranula in den Zellen der Malpighischen Gefäße von Periplaneta americana L
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Article
Bone marking and lead intoxication
Hitherto osteoclasts have not been studied in relation to lead intoxication after a single intravenous lead acetate injection. In this study a dose of no more than 4 mg/kg body weight provoked the origin of ch...
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Article
The contribution of a chloride shunt to the transmucosal potential of the rabbit submaxillary duct
Chloride movement across the wall of the rabbit submaxillary duct has been studied. It was shown that the chloride diffusion from blood to luminal side was determined primarily by the existing transmucosal pot...
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Article
Microtubules in Pneumocystis carinii
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New aspects of the life cycle of Pneumocystis carinii
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Article
Histochemistry of the juxtaglomerular apparatus in the toad Bufo bufo
An investigation regarding the question of whether there exists a macula densa as part of the juxtaglomerular apparatus in the kidney of amphibians has been carried out. With the aid of a histochemical reactio...
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Chapter
Intracellular transport and secretion of proteins
Ultrastructural studies have revealed a complex intracellular differentiation of eukaryotic cells. The interior is subdivided into a number of subcellular compartments, bounded by lipoprotein membranes with th...
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Article
Developmental biology of Pneumocystis carinii, an alternative view on the life cycle of the parasite
In this paper we present, based on elaborate ultrastructural studies, data on the existence of both intracellular and extracellular stages of Pneumocystis carinii, which result in a proposal of a new life cycle o...
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Article
Recurrent exertional rhabdomyolysis and stunted growth
A boy with recurrent exertional rhabdomyolysis and stunted growth is described. Fetal movements were few and the boy was small for gestational age. He always experienced easy fatigability, and he, noted bouts ...
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Article
Chronic mild diarrhoea, stunted growth and neuromuscular abnormalities
This report describes a 3 year-old girl with signs of ventricular hypertrophy, short stature, and persistent diarrhoea (without steatorrhoea or creatorrhoea) which was resistant to therapy. There was no clinic...
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Article
Ophthalmoplegia-plus
The four patients present an almost identical picture based on clinical, morphological and biochemical examination. The condition begins in the external ocular muscles and affects further the other cranial and...
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Article
Muscle phosphorylase deficiency in childhood
Myophosphorylase deficiency (McArdle's syndrome) is an uncommon conditon characterized by exercise intolerance, muscle cramps and myoglobinuria. The present report describes the clinical, histochemical, electr...
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Article
Percutaneous needle biopsy of skeletal muscle in childhood
The results of needle biopsies of skeletal muscle in 95 infants (age-range 2/12-17 1/12 year) are presented. The biopsies were carried out using the Vondra-needle. In all but one case an amount of material was...
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Article
Successful carnitine treatment in a non-carnitine-deficient lipid storage myopathy
An 18-month-old boy presented with general hypotonia, decreased muscle strength, retarded motor development and stunted growth. The excretion of dicarboxylic acids was enhanced. EMG was normal. A muscle biopsy...
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Article
Estimation of energy metabolism in human skeletal muscle homogenate as a diagnostic aid
A method is presented for thein vitro testing of the energy metabolism of human skeletal muscle. The levels of creatine phosphate, ATP, ADP and AMP, which are defined by the activity of many enzyme systems, are m...
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Chapter
Surface Ultrastructure of the Uterine Cervix and Early Detection of Irreversible Neoplasia
The plasma membrane-cell surface complex is of crucial significance for the social behavior of cells within cell populations (Nicolson 1977; Poste 1977; Nicolson et al. 1977). Alterations in cell surface organ...
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Article
Kearns syndrome: A heterogeneous group of disorders with CPEO, or a nosological entity?
In connection with 4 new cases of Kearns syndrome (multisystem form of mitochondrial CPEO), the condition was found to be present in slight to oligosymptomatic form in all 4 families. The marker symptom in sub...
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Article
Dysmyelination and disturbed metabolism of pyruvate: a case report
A patient with dysmyelination is described. Lactate levels were elevated in serum, urine, and cerebrospinal fluid. A decreased pyruvate oxidation rate due to a pyruvate dehydrogenase complex deficiency was dem...
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Article
A mitochondrial myopathy with a defective respiratory chain and carnitine deficiency
A boy presented suffering from generalised weakness, exercise intolerance and lactic acidosis. The weakness became evident at 2 years. A cerebral CT-scan showed cerebellar atrophy and central and peripheral at...
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Article
Deficiency of cytochromes b and aa3 in muscle from a floppy infant with cytochrome oxidase deficiency
A girl was presented suffering from generalised weakness and cardiorespiratory insufficiency. She succumbed at the age of 5 months. Lactate levels were elevated in serum, cerebrospinal fluid and urine. Histopa...