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  1. Article

    Open Access

    Anti-tumour effects and pharmacokinetic profile of 17-(5′-isoxazolyl)androsta-4,16-dien-3-one (L-39) in mice: an inhibitor of androgen synthesis

    17-(5′-Isoxazolyl)androsta-4,16-dien-3-one (L-39), a novel androstene derivative, was synthesized and evaluated in vitro and in vivo. L-39 showed potent and non-competitive inhibition of human testicular micro...

    I P Nnane, B J Long, Y-Z Ling, D N Grigoryev, A M Brodie in British Journal of Cancer (2000)

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