10 Result(s)
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A Eriksson
Biomedicine
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Article
Open AccessDrug screen in patient cells suggests quinacrine to be repositioned for treatment of acute myeloid leukemia
To find drugs suitable for repositioning for use against leukemia, samples from patients with chronic lymphocytic, acute myeloid and lymphocytic leukemias as well as peripheral blood mononuclear cells (PBMC) w...
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Article
Open AccessThe novel tyrosine kinase inhibitor AKN-028 has significant antileukemic activity in cell lines and primary cultures of acute myeloid leukemia
Aberrantly expressed tyrosine kinases have emerged as promising targets for drug development in acute myeloid leukemia (AML). We report that AKN-028, a novel tyrosine kinase inhibitor (TKI), is a potent FMS-li...
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Article
The expression of androgen receptors in human neck and limb muscles: effects of training and self-administration of androgenic-anabolic steroids
The purpose of this study was to investigate the immunohistochemical expression of androgen receptors (AR) in human vastus lateralis and trapezius muscles and to determine whether long-term strength training a...
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Article
Smoothelin in adult and develo** human arteries and myocardium
The aim of this investigation was to study, with immunohistochemical methods, the distribution of the novel cytoskeletal protein smoothelin in human cardiovascular tissues, the possible changes during the deve...
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Region Dependent Distribution of Muscle Fibre Types and Muscle Spindles in the Human Masseter Muscle Studied in Cross-Sections of Whole Muscle
Human masseter is divided anatomical into superficial and deep parts, but regional specialisation in the distribution of fibre types and muscle spindles is organised differently. Thus, the anterior part is pre...
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Article
Evidence of fibre hyperplasia in human skeletal muscles from healthy young men?
Cross-sections (thickness 10 μm) of whole autopsied left and right anterior tibialis muscles of seven young previously healthy right-handed men (mean age 23 years, range 18–32 years) were prepared for light-mi...
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Article
Incidence of early onset group B streptococcal septicemia in Sweden 1973 to 1985
A retrospective investigation was made to determine the incidence of early onset group B streptococcal (GBS) septicemia in Sweden in relation to perinatal data. During the period 1973–1985 the yearly incidence...
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Article
Human papillomavirus type 13 DNA in focal epithelial hyperplasia among Mexicans
Human papillomavirus (HPV) type 13 DNA was detected in focal epithelial hyperplasia lesions of the oral mucosa in seven half-caste mexicans. The lesions contained intracellular papillomavirus-like particles wi...
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Article
A possible new locus of alkaline phosphatase expressed in human testis
Human testes contain trace amounts of heat-stable placental-like alkaline phosphatase. Using a recently described allotype-specific monoclonal antibody (F11) toward placental alkaline phosphatase (PLAP), we show ...
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Article
The conduction system in the human heart at midgestation-immunohistochemical demonstration of the intermediate filament protein skeletin
The intermediate filaments have during recent years increasingly attracted attention and new information on the distribution of the subunits of the filaments has become available by the use of specific antibod...
