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Article
Defective Cytokine Expression but Adult-Type T-Cell Receptor, CD8, and p56lck Modulation in CD3− or CD2-Activated T Cells from Neonates
ABSTRACT: Expression of IL-2, interferon-γ, and IL-3 mRNA and proteins was investigated in peripheral blood mononuclear cells from cord blood after activation with phytohemagglutinin, CD2, or CD3 MAb. The resu...
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Article
Utilisation of Anti Lymphocyte Globulin in 57 Unrelated Bone Marrow Transplantations in Children
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Article
Outcome of unrelated bone marrow donor searches in 174 children resulting in 45 patients transplanted in the HLA-matched and -mismatched situation
The aim of the study was to evaluate the outcome of unrelated bone marrow donor (UBMD) searches initiated for 174 children between 1986 and 1997. Seven patients were registered twice so that a total of 181 UBM...
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Article
Alloreaction increases or restores CD40, CD54, and/or HLA molecule expression in acute myelogenous leukemia blasts, through secretion of inflammatory cytokines: dominant role for TNFβ, in concert with IFNγ
We have previously reported that alloreaction can lead to activation of dendritic cells through secretion of inflammatory cytokines. Here, we addressed whether alloreaction-derived cytokines may also lead to a...
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Article
Mesenchymal stem cells protect NOD mice from diabetes by inducing regulatory T cells
Displaying immunomodulatory capacities, mesenchymal stem cells (MSCs) are considered as beneficial agents for autoimmune diseases. The aim of this study was to examine the ability of MSCs to prevent autoimmune...