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  1. Article

    Open Access

    Individual caspase-10 isoforms play distinct and opposing roles in the initiation of death receptor-mediated tumour cell apoptosis

    The cysteine protease caspase-8 is an essential executioner of the death receptor (DR) apoptotic pathway. The physiological function of its homologue caspase-10 remains poorly understood, and the ability of ca...

    A Mühlethaler-Mottet, M Flahaut, K Balmas Bourloud, K Nardou in Cell Death & Disease (2011)