5 Result(s)
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Ádám Novák
Microarrays
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Article
Open AccessEfficient representation of uncertainty in multiple sequence alignments using directed acyclic graphs
A standard procedure in many areas of bioinformatics is to use a single multiple sequence alignment (MSA) as the basis for various types of analysis. However, downstream results may be highly sensitive to the ...
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Article
Open AccessQuantifying variances in comparative RNA secondary structure prediction
With the advancement of next-generation sequencing and transcriptomics technologies, regulatory effects involving RNA, in particular RNA structural changes are being detected. These results often rely on RNA s...
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Article
Open AccessCharacterising RNA secondary structure space using information entropy
Comparative methods for RNA secondary structure prediction use evolutionary information from RNA alignments to increase prediction accuracy. The model is often described in terms of stochastic context-free gra...
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Article
Open AccessReticular alignment: A progressive corner-cutting method for multiple sequence alignment
In this paper, we introduce a progressive corner cutting method called Reticular Alignment for multiple sequence alignment. Unlike previous corner-cutting methods, our approach does not define a compact part o...
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Article
Open AccessHow reliably can we predict the reliability of protein structure predictions?
Comparative methods have been the standard techniques for in silico protein structure prediction. The prediction is based on a multiple alignment that contains both reference sequences with known structures and t...
