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455 Result(s)
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Article
Construction and screening of a multi-point site-specific mutant library of subtilisin E with a set of oligonucleotides
A mutant library of subtilisin E containing random combinations of various mutagenized sites was constructed by one-round mutagenesis with 15 mutagenic oligonucleotides. Mutants were screened through dot blot ...
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Article
Mixture of HIBA and glycolic acid as eluent for effective separation of yttrium and dysprosium by HPLC
A mixture of 2-hydroxy-2-methylpropanoic acid (HIBA) and glycolic acid, with 1-octanesulfonate (OS) as hydrophobic ion proved to be successful for the separation of rare-earth elements (REE). If the ratio of ...
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Article
Immunohistochemical study of NGF and its receptors in the synovial membrane of the ankle joint of adjuvant-induced arthritic rats
To study the role of nerve growth factor (NGF) in local inflammation, we investigated the expression of NGF and its receptors, trkA and p75, in the ankle joints of adjuvant-induced arthritic rats. Infiltrated...
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Article
Involvement of sensory nerves and immune cells in osteophyte formation in the ankle joint of adjuvant arthritic rats
To study the mechanism of osteophyte formation in the ankle joints of adjuvant arthritic (AA) rats, the localization of peripheral nerves and immune cells in the synovia were investigated in both axotomized A...
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Article
A novel cDNA encodes a putative hRALY-like protein, hRALYL
High throughput cDNA sequencing and 5′-rapid amplification of cDNA ends (5′RACE) isolated two cDNAs that shared the same open reading fragment (ORF). Northern blot analysis with the fetal brain mRNA blots dete...
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Article
Effect of the resection of the sciatic nerve on the Th1/Th2 balance in the synovia of the ankle joint of adjuvant arthritic rats
Inflamed synovia of the ankle joint after 2–4 weeks of adjuvant injection receives dense sensory innervation. To study the role of sensory nerves on the local inflammation, the relative expression of T helper ...
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Article
Open AccessInduction of serine racemase expression and D-serine release from microglia by amyloid β-peptide
Roles for excitotoxicity and inflammation in Alzheimer's disease have been hypothesized. Proinflammatory stimuli, including amyloid β-peptide (Aβ), elicit a release of glutamate from microglia. We tested the p...
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Article
Regulation of osteoclastogenesis by Simon extracts composed of caffeic acid and related compounds: successful suppression of bone destruction accompanied with adjuvant-induced arthritis in rats
Simon extracts are vitamin K1-rich food materials extracted from the leaves of the Simon sweet potato. Although vitamin K is known to stimulate bone formation, we postulated that Simon extracts also contain unkno...
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Article
Bladder paraganglioma with a calculus: A case report
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Article
Reconsideration of the origin of the Yongming style and its relationship to the translation of Buddhist sutras
For several decades, scholars have expressed different opinions since Chen Yinque 陈寅恪 brought forward the viewpoint that the creation of Yongming style was influenced by the translation of Buddhist scriptures....
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Article
Open AccessModulation of microglial/macrophage activation by macrophage inhibitory factor (TKP) or tuftsin (TKPR) attenuates the disease course of experimental autoimmune encephalomyelitis
Myelin Oligodendrocyte Glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE) is the most commonly used mouse model for multiple sclerosis (MS). During the of progression of EAE, microglia,...
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Article
Synthesis and antitussive evaluation of verticinone-cholic acid salt, a novel and potential cough therapeutic agent
To seek a novel and potent antitussive drug based on Shedan—Chuanbei powder, a complex of traditional Chinese medicine preparation for cough therapy.
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Article
Analysis of hupehenine in the total alkaloids from Fritillaria hupehensis by HPLC-ELSD
A reverse-phase high pressure liquid chromatography (HPLC) method with evaporative light scattering detection (ELSD) has been developed for the quantitative analysis of hupehenine in the total alkaloids from Frit...
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Article
Mathematical Model for Growth of Inclusion in Deoxidization on the Basis of Unreacted Core Model
Controlling inclusion composition, from the point of view of thermodynamics, only explains the probability and limit of reaction. However, kinetics makes the nucleation and the velocity of growth of inclusions...
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Addictive evaluation of cholic acid-verticinone ester, a potential cough therapeutic agent with agonist action of opioid receptor
The purpose of this work was to search for potential drugs with potent antitussive and expectorant activities as well as a low toxicity, but without addictive properties. Cholic acid-verticinone ester (CA-Ver)...
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Design of Silicon Resonant Micro Accelerometer Based on Electrostatic Rigidity
The structure characteristics and working principle of silicon resonant micro-accelerometer based on electrostatic rigidity are presented. Dynamic characteristics of double-ended tuning fork (DETF) in the sens...
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Article
Hypoxic training increases metabolic enzyme activity and composition of α-myosin heavy chain isoform in rat ventricular myocardium
Cardiac muscle adaptation is essential for maintaining physical capacity after ascending to high altitude. This study examines the effects of high altitude training on myocardial metabolic enzyme activity and ...
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Article
Open AccessDigenean parasites of Chinese marine fishes: a list of species, hosts and geographical distribution
In the literature, 630 species of Digenea (Trematoda) have been reported from Chinese marine fishes. These belong to 209 genera and 35 families. The names of these species, along with their hosts, geographical...
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Article
Unified analytical solutions for a circular opening based on non-linear unified failure criterion
Unified analytical solutions are presented for the predictions of the stresses and displacements around a circular opening based on non-linear unified failure criterion and the elastic-brittle-plastic softenin...
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Chemical constituents from the roots of Actinidia chinensis