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Article
Open AccessAuthor Correction: TLR agonists polarize interferon responses in conjunction with dendritic cell vaccination in malignant glioma: a randomized phase II Trial
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Article
Late Mesoproterozoic to Early Neoproterozoic Tectonic Evolution of the SW Yangtze Block, South China: Evidence from U-Pb Geochronology and Lu-Hf Isotopes of Detrital Zircons from Sedimentary Rocks
In situ zircon U-Pb geochronological and Lu-Hf isotope studies of detrital zircons from Late Mesoproterozoic to Early Neoproterozoic sedimentary units on the southwestern margin of the Yangtze Block have importan...
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Article
Silencing of the T-type voltage-gated calcium channel α1 subunit by fungus-mediated RNAi altered the structure of F-actin and caused defective behaviors in Ditylenchus destructor
T-type calcium channels, characterized as low-voltage activated (LVA) calcium channels, play crucial physiological roles across a wide range of tissues, including both the neuronal and nonneuronal systems. Usi...
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Article
Open AccessTLR agonists polarize interferon responses in conjunction with dendritic cell vaccination in malignant glioma: a randomized phase II Trial
In this randomized phase II clinical trial, we evaluated the effectiveness of adding the TLR agonists, poly-ICLC or resiquimod, to autologous tumor lysate-pulsed dendritic cell (ATL-DC) vaccination in patients...
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Article
CCDC92 promotes podocyte injury by regulating PA28α/ABCA1/cholesterol efflux axis in type 2 diabetic mice
Podocyte lipotoxicity mediated by impaired cellular cholesterol efflux plays a crucial role in the development of diabetic kidney disease (DKD), and the identification of potential therapeutic targets that reg...
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Article
Effect of RNA interference targeting chemosensory genes on chemotactic host-seeking in Meloidogyne graminicola
Pre-parasitic second-stage juveniles (pre-J2s) of Meloidogyne graminicola are non-feeding in soil, and their migration, localization and successful invasion of host roots are essential for survival. Chemotaxis is...
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Article
Mechanical Properties of Concentric Three-Phase HTS Cable Based on Laminated Theory
High-temperature superconducting (HTS) cable, with massive current carrying capability and low electric power loss, is always at the cutting edge of the strong electric fields. The concentric three-phase HTS c...
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Article
Open AccessStability and integrity of self-assembled bovine parvovirus virus‑like particles (BPV‑VLPs) of VP2 and combination of VP1VP2 assisted by baculovirus-insect cell expression: a potential logistical platform for vaccine deployment
Bovine parvovirus (BPV) is an autonomous DNA virus with a smaller molecular size and subtle differences in its structural proteins, unlike other animal parvoviruses. More importantly, this virus has the potent...
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Article
Higher risk of osteoporosis in adult-onset asthma than childhood-onset asthma: from genetic and prospective evidence
Both COA and AOA have a genetically causal effect on osteoporosis. COA and AOA were independently associated with incident osteoporosis, and the risk was greatly higher in AOA. Besides corticosteroids, the inc...
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Article
Author Correction: A second-generation M1-polarized CAR macrophage with antitumor efficacy
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Article
Biocontrol potential of Priestia megaterium YB-3 against Meloidogyne graminicola and its impact on the rhizosphere microbial community
Root-knot nematodes (Meloidogyne spp.) are highly destructive pests that cause enormous crop losses worldwide. With the increasing awareness of environmental protection, exploring the potential of biocontrol agen...
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Chapter and Conference Paper
Optimal Design and Landing Simulation of an Asteroid Probe with Variable Stiffness Legs
Attachment mechanisms are used and usually firmly connected to the main body of the asteroid probe to maintain the attitude and ensure the following sampling work. However, the probe with rigid connections has...
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Article
A lunar time scale from the perspective of the Moon’s dynamic evolution
A geologic time scale is a chronological system that separates the geological strata of a planetary body into different units in temporal sequence and shows its progressive evolution. The time scale of the Moo...
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Article
A second-generation M1-polarized CAR macrophage with antitumor efficacy
Chimeric antigen receptor (CAR) T cell therapies have successfully treated hematological malignancies. Macrophages have also gained attention as an immunotherapy owing to their immunomodulatory capacity and ab...
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Article
Open AccessA common East-Asian ALDH2 mutation causes metabolic disorders and the therapeutic effect of ALDH2 activators
Obesity and type 2 diabetes have reached pandemic proportion. ALDH2 (acetaldehyde dehydrogenase 2, mitochondrial) is the key metabolizing enzyme of acetaldehyde and other toxic aldehydes, such as 4-hydroxynone...
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Article
Open AccessEffect of body mass index on clinical outcomes after robotic cardiac surgery: is there an obesity paradox?
To investigate the effect of body mass index (BMI) on clinical outcomes after robotic cardiac surgery, and to explore the postoperative obesity paradox.
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Article
Performance of Two-phase Closed Loop Thermosyphon in Cooling Down of Compact Superconducting Magnet
An experiment to investigate the two-phase closed loop thermosyphon (TPCLT) to cooling the compact superconducting magnet has been performed. This study is motivated mainly by our development of cryogenic cool...
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Article
Zircon SHRIMP U-Pb Ages, Geochemistry and Nd-Hf Isotopes of ∼1.0 Ga A-Type Felsic Rocks in the Southwestern Yangtze Block, South China: Petrogenesis and Tectonic Implications
The petrogenesis and tectonic affinity of Late Mesoproterozoic igneous rocks in the Yangtze Block are important to understand its tectonic evolution within the context of the Rodinia supercontinent’s reconstru...
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Article
Open AccessThe earliest known artificial synthesized ε-Fe2O3 in the Deqing Kiln ceramic ware of Tang Dynasty
Metastable ε-Fe2O3 was discovered on a ceramic ware of Deqing kiln of the Tang Dynasty, which coexists with α-Fe2O3 in the brown area between adjacent black glaze areas, and it is the earliest known artificially ...
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Article
Ecological water replenishment to the Yongding River, China: effects of different water sources on inorganic ions and organic matter characteristics
Ecological water replenishment is considered to be an important project to adjust river ecosystems with water shortages and degradation, and its impact on the water quality of the target river section deserves...
