-
Article
A novel de-noising method for NMR echo data obtained from tight sandstone reservoirs
To improve the signal-to-noise ratio (SNR) of nuclear magnetic resonance (NMR) echo data with SNR below 8 obtained from tight sandstone reservoirs and improve the accuracy of the porosity obtained from ...
-
Article
Parallel Parking Path Planning and Tracking Control Based on Simulated Annealing Algorithm
To address the issues of curvature discontinuity and terminal tire non-return in the parallel parking of autonomous vehicles, a novel parallel parking path planning method based on the combination of the quint...
-
Article
Assessing the Association of Smoking and Alcohol Consumption With Chronic Pain in Depression and Anxiety Disorders
Previous studies have observed the protective effects of alcohol and the deleterious effects of smoking on chronic pain in the general population. Interestingly, alcohol and smoking were negatively associated ...
-
Article
Open AccessSystemic delivery of oncolytic herpes virus using CAR-T cells enhances targeting of antitumor immuno-virotherapy
Recent studies have indicated that combining oncolytic viruses with CAR-T cells in therapy has shown superior anti-tumor effects, representing a promising approach. Nonetheless, the localized delivery method o...
-
Article
KDM1A, a potent and selective target, for the treatment of DNMT3A-deficient non-small cell lung cancer
DNMT3A is a crucial epigenetic regulation enzyme. However, due to its heterogeneous nature and frequent mutation in various cancers, the role of DNMT3A remains controversial. Here, we determine the role of DNM...
-
Article
Responsive mechanism of Hemerocallis citrina Baroni to complex saline-alkali stress revealed by photosynthetic characteristics and antioxidant regulation
Saline-alkali stress induces oxidative damage and photosynthesis inhibition in H. citrina, with a significant downregulation of the expression of photosynthesis- and antioxidant-related genes at high concentratio...
-
Article
Ecosystem-level response to complex disturbances of an interconnected river–lake system based on Ecopath model over the last 30 years
Freshwater ecosystems have been severely disturbed in recent years. However, our understanding of the ecosystem-level changes within freshwater food webs under complex disturbances is still limited. To address...
-
Article
Open AccessVitamin D is involved in the effects of the intestinal flora and its related metabolite TMAO on perirenal fat and kidneys in mice with DKD
Vitamin D was shown to directly exert a protective effect on diabetic kidney disease (DKD) in our previous study. However, whether it has an effect on perirenal adipose tissue (PRAT) or the intestinal flora an...
-
Article
Can Industrial Structure Upgrading Restrain Industrial Land Expansion? Evidence from China
China has made great achievements in industrial development and is transforming into a powerful manufacturing country. Meanwhile, the industrial land scale is also expanding. However, whether industrial struct...
-
Article
Assessing the joint effects of mitochondrial genes and physical activity on the psychiatric phenotype of subjective well-being based on the UK Biobank data
Subjective well-being (SWB) is an important measure for mental health status. Previous research has shown that physical activity can affect an individual’s well-being, yet the underlying molecular mechanism re...
-
Article
Wogonin preconditioning of MSCs improved their therapeutic efficiency for colitis through promoting glycolysis
Inflammatory bowel diseases (IBDs) are prevalent and debilitating diseases with limited clinical treatment strategies. Mesenchymal stem cell (MSCs) are pluripotent stem cells with self-renewal capability and m...
-
Article
Are Callings Always Ethically Good? Why and When Occupational Calling Inhibits Unethical Decision-Making Among Researchers
In recent years, attention to researchers’ scientific misconduct has increased dramatically. Although existing research reflects a shared value that occupational calling is an ethical good (i.e., being more li...
-
Article
Open AccessRepurposing non-pharmacological interventions for Alzheimer's disease through link prediction on biomedical literature
Non-pharmaceutical interventions (NPI) have great potential to improve cognitive function but limited investigation to discover NPI repurposing for Alzheimer's Disease (AD). This is the first study to develop ...
-
Article
Open AccessExperiment and modelling of texture and sliding direction dependence on finger friction behavior
Humans rely on their fingers to sense and interact with external environment. Understanding the tribological behavior between finger skin and object surface is crucial for various fields, including tactile per...
-
Article
Reclassification of therapeutic response of unresectable hepatocellular carcinoma to anti-angiogenic therapy and immunotherapy using alpha RECIST
To assess the therapeutic response of HCC to antiangiogenic therapy plus immunotherapy by integrating RECIST 1.1 and alpha-fetoprotein (AFP) response at the 6th week to predict overall survival (OS).
-
Article
Comparison and optimization of b value combinations for diffusion-weighted imaging in discriminating hepatic fibrosis
Diffusion-weighted imaging (DWI) has shown potential in characterizing hepatic fibrosis. However, there are no widely accepted apparent diffusion coefficient (ADC) values for the b value combination. This study a...
-
Article
Open AccessWind tunnel test on low-rise buildings influenced by hillside height in typical mountain terrain
Hills and mountain fields have a high proportion in coastal areas around the world. Especially in China, lots of low-rise buildings are in complex mountain terrain. Compared with the flat topography under typh...
-
Article
The impact of family pressure on entrepreneurial intention: an empirical study based on Chinese entrepreneurs
Family pressure can influence individuals to make entrepreneurial decisions. This study examined the relationship between personal family pressure and entrepreneurial intention. We contend that this relationsh...
-
Article
Open AccessKeto-anthraquinone covalent organic framework for H2O2 photosynthesis with oxygen and alkaline water
Hydrogen peroxide photosynthesis suffers from insufficient catalytic activity due to the high energy barrier of hydrogen extraction from H2O. Herein, we report that mechanochemically synthesized keto-form anthraq...
-
Article
Open AccessMolecular mechanisms and regulation of recombination frequency and distribution in plants
Recent developments in understanding the distribution and distinctive features of recombination hotspots are reviewed and approaches are proposed to increase recombination frequency in coldspot regions.
