12,582 Result(s)
within
**xi Ma
Life Sciences
English
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Article
Open AccessDNA methylation age acceleration contributes to the development and prediction of non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is prevalent in the aging society. Despite body weight reduction, the prevalence of NAFLD has been increasing with aging for unknown reasons. Here, we investigate the ...
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Open AccessMiR-425-5p suppression of Crebzf regulates oocyte aging via chromatin modification
Female infertility due to declining oocyte quality with age remains a significant challenge for patients and physicians, despite extensive research efforts. Recent studies suggest that microRNAs (miRNAs), whic...
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Leaf area index estimation in maize and soybean using UAV LiDAR data
Leaf area index (LAI) is a vital input variable for crop growth and yield prediction models. Therefore, rapid and accurate crop LAI estimates can offer important information for monitoring and managing the qua...
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Open AccessPublisher Correction: Restrained Mitf-associated autophagy by Mulberroside A ameliorates osteoclastogenesis and counteracts OVX-Induced osteoporosis in mice
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Correction: lncRNA THAP7-AS1, transcriptionally activated by SP1 and post-transcriptionally stabilized by METTL3-mediated m6A modification, exerts oncogenic properties by improving CUL4B entry into the nucleus
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Open AccessAuthor Correction: Self-administered mindfulness interventions reduce stress in a large, randomized controlled multi-site study
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Open AccessDeath associated protein like 1 acts as a novel tumor suppressor in melanoma by increasing the stability of P21 protein
Melanoma is a primary malignant tumor with high lethality, which occurs in the skin and eye tissues, while the molecular mechanisms of melanomagenesis remain largely unknown. Here, we show that death-associate...
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Open AccessEvaluation of vaccine candidates against Rhodococcus equi in BALB/c mice infection model: cellular and humoral immune responses
Rhodococcus equi (R. equi) is a zoonotic opportunistic pathogen that mainly causes fatal lung and extrapulmonary abscesses in foals and immunocompromised individuals. To date, no commercial vaccine against R. equ...
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Cold tolerance SNPs and candidate gene mining in the soybean germination stage based on genome-wide association analysis
Three QTLs associated with low-temperature tolerance were identified by genome-wide association analysis, and 15 candidate genes were identified by haplotype analysis and gene expression analyses.
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Growth and Transcriptional Regulation of Camellia sinensis Planted in Understory Mode Revealed by Transcriptomic, Metagenomic, and Machine-Vision Analyses
Camellia sinensis is a significant economic and medical plant. The plant is short and thrives in shaded environments, making it suitable for cultivation under forest canopies. However, the mechanisms governing th...
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Open AccessRole of the V2R–βarrestin–Gβγ complex in promoting G protein translocation to endosomes
Classically, G protein-coupled receptors (GPCRs) promote signaling at the plasma membrane through activation of heterotrimeric Gαβγ proteins, followed by the recruitment of GPCR kinases and βarrestin (βarr) to...
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Open AccessTracking the hologenome dynamics in aquatic invertebrates by the holo-2bRAD approach
The “hologenome” concept is an increasingly popular way of thinking about microbiome-host for marine organisms. However, it is challenging to track hologenome dynamics because of the large amount of material, ...
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Open AccessNew advances in drug development for metabolic dysfunction-associated diseases and alcohol-associated liver disease
Metabolic disorders are currently threatening public health worldwide. Discovering new targets and develo** promising drugs will reduce the global metabolic-related disease burden. Metabolic disorders primar...
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Responses of Robinia pseudoacacia co-inoculated with rhizobia and arbuscular mycorrhizal fungi to cadmium under nitrogen excess condition
Rhizobia and arbuscular mycorrhizal fungi (AMF) are important symbiotic microorganisms promoting plant growth in contaminated soils. This study aims to determine whether the new microbial communities construct...
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Open AccessHuman cytomegalovirus infection impairs neural differentiation via repressing sterol regulatory element binding protein 2-mediated cholesterol biosynthesis
Congenital human cytomegalovirus (HCMV) infection is a major cause of abnormalities and disorders in the central nervous system (CNS) and/or the peripheral nervous system (PNS). However, the complete pathogene...
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Sensitivity of aggregate-associated soil organic carbon and total nitrogen to abandonment of paddy soil in subtropical China
Abandonment of paddy fields is a significant threat to soil organic carbon (SOC) stocks owing to the associated shift from anaerobic to aerobic conditions. However, the impact of this transition on the dynamic...
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Extracellular vesicles derived from “serum and glucose” deprived HUCMSCs promoted skin wound healing through enhanced angiogenesis
Extracellular vesicles (EVs) produced from MSCs were currently considered as a novel therapeutic agent for skin tissue regeneration and repair. Preconditioning stem cells may activate more molecular pathways a...
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Open AccessMolting in early Cambrian armored lobopodians
Lobopodians represent a key step in the early history of ecdysozoans since they were the first animals to evolve legs within this clade. Their Cambrian representatives share a similar body plan with a typicall...
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Open AccessGlucose-montmorillonite hydrochar composite activating peroxymonosulfate for sulfentrazone rapid degradation and phytotoxicity alleviation to rice
Sulfentrazone is an excellent herbicide for the control of broad-leaved weeds and some grasses. However, its herbicidal residues pose potential risks to the environment. The use of carbonaceous materials as ca...
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Open AccessA comprehensive review of computational cell cycle models in guiding cancer treatment strategies
This article reviews the current knowledge and recent advancements in computational modeling of the cell cycle. It offers a comparative analysis of various modeling paradigms, highlighting their unique strengt...
