1,023 Result(s)
-
Article
Open AccessAn investigation of the molecular characterization of the tripartite motif (TRIM) family and primary validation of TRIM31 in gastric cancer
Most TRIM family members characterized by the E3-ubiquitin ligases, participate in ubiquitination and tumorigenesis. While there is a dearth of a comprehensive investigation for the entire family in gastric ca...
-
Article
Long-time Asymptotics for the Reverse Space-time Nonlocal Hirota Equation with Decaying Initial Value Problem: without Solitons
In this work, we mainly consider the Cauchy problem for the reverse space-time nonlocal Hirota equation with the initial data rapidly decaying in the solitonless sector. Start from the Lax pair, we first const...
-
Article
Is obedience rewarding? State investment in response to CSR reporting in China
Scholars have recognized governmental and political influences on corporate social responsibility (CSR) reporting activities. However, whether such activities subsequently result in governmental support to fir...
-
Article
Preparation of nitrogen-enriched Fe-doped porous biochar using the catalytic pyrolysis of paper mill sludge
Paper mill sludge (PMS) is an abundant organic solid waste with complex composition from the pulp and paper industry. In this study, the Fe2O3 was used as a catalyst during PMS pyrolysis to reduce the emission of...
-
Article
A facile strategy to construct MOF-based nanocatalyst with enhanced activity and selectivity in oxytetracycline degradation
Recently, many efforts have been dedicated to construct artificial catalysts with enzyme-like activity. However, it is still a big challenge to endow artificial catalysts with specific substrate selectivity. I...
-
Article
Metabolic obesity phenotypes and all-cause mortality among the Chinese oldest-old population: a prospective cohort study
The obesity paradox has been reported among older adults. However, whether the favorable effect of obesity is dependent on metabolic status remains largely unknown. We aimed to explore the association of metab...
-
Article
Author Correction: ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway
-
Article
Evaluation of combined epiretinal membrane removal with intravitreal triamcinolone injection utilizing ectopic inner foveal layer staging scheme
To investigate the macular morphological and visual outcomes of combined idiopathic epiretinal membrane (iERM) removal with triamcinolone acetonide (TA) injection based on consideration of the ectopic inner fo...
-
Article
Open AccessChanges in temporal lobe activation during a sound stimulation task in patients with sensorineural tinnitus: a multi-channel near-infrared spectroscopy study
The subjective sign of a serious pandemic in human work and life is mathematical neural tinnitus. fNIRS (functional near-infrared spectroscopy) is a new non-invasive brain imaging technology for studying the n...
-
Article
Open AccessTaxane combined with lobaplatin or anthracycline for neoadjuvant chemotherapy of triple-negative breast cancer: a randomized, controlled, phase II study
Previous studies have shown that the addition of platinum to neoadjuvant chemotherapy (NAC) improved outcomes for patients with triple-negative breast cancer (TNBC). However, no studies have assessed the effic...
-
Article
EP300 promotes tumor stemness via epigenetic activation of CRISP3 leading to lobaplatin resistance in triple-negative breast cancer
Lobaplatin shows antitumor activity against a wide range of tumors, including triple-negative breast cancer (TNBC), and has been linked to cancer stem cell pool. Here, we investigated the molecular mechanisms ...
-
Article
Lifting the Veil: Using a Spatial Discontinuity to Assess the Impact of National Development Zones on Upgrading of Chinese Manufacturing
Using a spatial discontinuity created by geographic boundary lines, this paper evaluates the incidence and effectiveness of a prominent place-based policy in China: national development zones (NDZs). Combining...
-
Article
Low NDRG2, regulated by the MYC/MIZ-1 complex and methylation, predicts poor outcomes in DLBCL patients
Diffuse large B-cell lymphoma (DLBCL) represents the most common tumor in non-Hodgkin’s lymphoma. N-Myc downstream-regulated gene 2 (NDRG2) is a tumor suppressor highly expressed in healthy tissues but downreg...
-
Article
Callus-specific CRISPR/Cas9 system to increase heritable gene mutations in maize
A callus-specific CRISPR/Cas9 (CSC) system with Cas9 gene driven by the promoters of ZmCTA1 and ZmPLTP reduces somatic mutations and improves the production of heritable mutations in maize.
-
Article
Open AccessConstructing a prognostic model for colorectal cancer with synchronous liver metastases after preoperative chemotherapy: a study based on SEER and an external validation cohort
The combination of preoperative chemotherapy and surgical treatment has been shown to significantly enhance the prognosis of colorectal cancer with liver metastases (CRLM) patients. Nevertheless, as a result o...
-
Article
Edge Electronic States and Direct Bandgap in Si Nanostructures on Silicon Oxide
The nanostructures on silicon oxide, as a new phase of matter, only allows conducting electrons to exist on its surfaces, in which the edge electronic states dramatically provide intriguing insights into the w...
-
Article
Defect engineered nickel hydroxide nanosheets for advanced pseudocapacitor electrodes
While the past years have witnessed great achievement in pseudocapacitors, the inauguration of electrode materials of high-performance still remains a formidable challenge. Moreover, the capacity and rate capa...
-
Article
Design of Z-fiber Guiding Needle for Composite Material Preform with Large-Thickness and High-Density
Traditional carbon fiber reinforced carbon matrix composites are mostly two-dimensional laminated structures with low interlayer properties. Z-fiber reinforcement technology can improve the properties of compo...
-
Article
Clinical Outcomes On Tubridge Flow Diverter in Treatmenting Intracranial Aneurysms: a Retrospective Multicenter Registry Study
In China, the application of nitinol Tubridge flow diverter (TFD) has become popular for treating intracranial aneurysms (IAs). In this study, we investigated the safety outcomes of the application of TFD for ...
-
Article
A nomogram model for predicting the efficacy of cyclosporine in patients with pure red cell aplasia
Pure red cell aplasia (PRCA) is a rare bone marrow disorder characterized by a severe reduction or absence of erythroid precursor cells, without affecting granulocytes and megakaryocytes. Immunosuppressive the...
