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  1. Article

    Open Access

    Antitumor activity of selective MEK1/2 inhibitor AZD6244 in combination with PI3K/mTOR inhibitor BEZ235 in gefitinib-resistant NSCLC xenograft models

    Although the EGF receptor tyrosine kinase inhibitors (EGFR-TKI) gefitinib have shown dramatic effects against EGFR mutant lung cancer, patients become resistant by various mechanisms, including gatekeeper EGFR-T7...

    Yiqing Qu, **uxiu Wu, Yunhong Yin, Yan Yang… in Journal of Experimental & Clinical Cancer … (2014)

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